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Could sound waves be used to treat cocaine addiction? A UVA study aims to find out

By stimulating a part of the brain linked to addiction, UVA scientists hope to eliminate cravings in cocaine addicts.
UVA
By stimulating a part of the brain linked to addiction, UVA scientists hope to eliminate cravings in cocaine addicts.

Doctors can prescribe effective treatments for heroin and opioid addiction, but there’s no medication to help cocaine addicts quit. That’s why doctors at the University of Virginia are trying a whole new approach – stimulating part of the brain that’s linked to addiction.

With a $5 million grant from the National Institute on Drug Abuse, scientists at the University of Virginia will soon begin a study using soundwaves to stimulate a part of the brain known as the insula. The idea was sparked by patients who were addicted to cigarettes until they suffered a stroke that disrupted insular function.

Dr. Nassima Ait-Daoud heads UVA's Center for Leading Edge Addiction Research and is the lead on a study of whether focused ultrasound could reduce or eliminate cravings in people addicted to cocaine.
UVA
Dr. Nassima Ait-Daoud heads UVA's Center for Leading Edge Addiction Research and is the lead on a study of whether focused ultrasound could reduce or eliminate cravings in people addicted to cocaine.

“These are people who were heavy smokers regularly, had a stroke and woke up saying, ‘I have no craving. I have no desire. It is gone!’”

Dr. Nassima Ait-Daoud will lead the study of 40 patients.

“We will subject our participants to pictures of cocaine, people using cocaine and will connect them to functional MRI to really see where the brain is lighting up.”

Then, they’ll stimulate the insula with low-intensity focused ultrasound and test again. They hope to find out whether it reduces cravings for the drug and, if so, how long the effect lasts.

For more information on the study, call 434-243-0541.

This report, provided by Virginia Public Radio, was made possible with support from the Virginia Education Association.

Updated: August 24, 2023 at 10:41 AM EDT
Editor's Note: The University of Virginia is a financial supporter of Radio IQ.
Sandy Hausman is Radio IQ's Charlottesville Bureau Chief