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Back in 2005, Heath Ledger and Jake Gyllenhaal captured lust shading into love, and love decaying into heartbreak. The movie got a lot of things right — but not everything.

Three scientists learned they carry genes that dramatically increase their risk for Alzheimer's disease. Now they're working to keep their brains healthy.

President Obama's trip to Africa comes at a time of increasing African economic growth and declining U.S. influence on the continent. To be successful, he will need to overcome a general perception that the United States has withdrawn from Africa. At the same time, he must convince an American public and private sector that getting more invested in Africa will be good for American jobs and the economy.

Think buying health insurance through the Affordable Care Act will be confusing? You're not alone. NPR listeners asked questions that have been bugging them about state insurance exchanges and other new options. NPR health policy correspondent Julie Rovner explains how it's going to work.

Two of San Francisco Bay Area Rapid Transit's largest unions went on strike after weekend talks with management failed to produce a new contract. The move ensures a nightmarish journey ahead for Monday commuters.

Creditors are going to lose up to 70 cents of every dollar they're owed by Jefferson County, Ala. The county earned the title of largest municipal bankruptcy in U.S. history after a sewer financing deal went awry.

NPR's A Martinez speaks with legendary HBO boxing commentator Jim Lampley about Friday's unconventional bout between former champ Mike Tyson and social media star Jake Paul.

Across the country, Muslim prison chaplains are in short supply. A new program offers classes to Muslim inmates designed to use faith as a pathway to rehabilitation and reentry.

Rebecca Paul Hargrove, who created two state lotteries and now runs a third, understands what makes a lottery program work.

Brad Duke won $220 million in the lottery in 2005. Duke talks about the moment he realized he'd won, and how his life changed after winning.